Liver Regeneration


Pierre-Alain Clavien, MD, PhD

Our laboratory made the discovery of serotonin as a key mediator of liver regeneration and pathogenesis of cancer (Science 2008).


New Project: Temporary Portal Vein Occlusion and Liver Regeneration

The aims of this project were

  1. to assess the efficacy of temporary portal vein embolization (PVE) compared to permanent occlusion of the portal vein with embospheres or portal vein ligature (PVL) on hypertrophy of the non-embolized liver lobes;
  2. to assess histological and functional recovery of embolized liver lobes after temporary and permanent PVE.